Author: Admin

Saturday, September 12, 2009

A World Health Organisation study published in The Lancet has revealed the main causes of death for people aged 10–24. It has described the majority of these deaths as preventable and suggested solutions to the problems.

97% of the 2.6 million fatalities annually occur in low- and middle-income countries. The age group comprises 1.8 billion people, 30% of the total population. 15% of female deaths were down to “maternal mortality” which included pregnancy complications, unsafe abortions, and mutilation of genitals. Road traffic accidents accounted for 10% of deaths.

6.3% of the deaths were suicides and 6% were down to violence. Tuberculosis and similar lung infections took 10% of the lives and HIV/AIDS killed 5.5%. Most of the deaths were in sub-Saharan Africa and Southeast Asia. Africa and Southeast Asia were also the only places where male deaths were not above those of females, as much of the maternal mortality occurred there. The data came from 2004.

In developed countries, 32% of the deaths were down to road accidents. “There has long been an assumption that young people are healthy, fit and they don’t die,” explained the report’s lead author, Australian children’s health expert George Patton. He goes on to say “I’ve certainly heard politicians and policy-makers make statements of that kind… Some of these problems, related to emotion, are actually very prominent causes not only of death in adolescence, but health problems later in life.”

The study said safer speed limits, more use of helmets and seatbelts, and better enforcement of drunk driving law could greatly curb the road deaths. Maternal deaths and sexually transmitted disease rates could be cut by sexual education, safe abortion clinics, pregnancy support, HIV testing and treatment, and access to contraceptives.

Violence and suicide could be reduced by education in life skills and an improved role of parents, the study found. It also sought reduction of availability of poisons, firearms, and other dangerous items. In the case of suicide, the study said more work was needed to help young people recover from acts of violence, sexual assault, and child abuse in both the short and long term. Alcohol access reduction was also requested.

The study was conducted by University College London’s Russell Viner, World Health Organization’s Krishna Bose and George Patton of the Royal Children’s Hospital in Melbourne, Australia.

Wednesday, December 7, 2005

Australian researchers say they have scientifically proven that stress causes sickness. The Garvan Institute in Sydney has discovered that a hormone, known as neuropeptide Y (NPY) is released into the body during times of stress. Their findings show the hormone can stop the immune system from functioning properly.

“Neuropeptide Y is one of those hormones that gets unregulated or released from neurones when stressful situations occur…it’s known for example that it regulates blood pressure and heart rates so your heart rate goes up but it hasn’t been known that it actually can affect immune cells as well,” said Professor Herbert Herzog, one of the researchers.

Herzog feels it is good to finally have proof of something people have suspected for so long.

“Now we have proven without doubt that there is a direct link and that stress can weaken the immune system and that makes you more vulnerable when you for example have a cold or flu and even in the more serious situations such as cancer can be enhanced in these situations,” said Herzog.

The Garvan Institute study centres on two key events that enable the human body to recognise foreign substances and control invaders. When our body encounters a pathogen (bacteria and viruses), the immune cells retain and interrogate suspects. Their activation is made possible by NPY. These cells then return to the lymph nodes, which are found all over the body, with information about the foreign invaders. The lymph nodes are where decisions about defence are made.

“Most of us expect to come down with a cold or other illness when we are under pressure, but until now we have mostly had circumstantial evidence for a link between the brain and the immune system,” said lead Garvan researcher, associate Professor Fabienne Mackay. “During periods of stress, nerves release a lot of NPY and it gets into the bloodstream, where it directly impacts on the cells in the immune system that look out for and destroy pathogens (bacteria and viruses) in the body.”

In the case of bacteria and viruses, TH1 cells are part of the attack team that is sent out on the ‘search and destroy’ mission. But when their job is done they need to be turned ‘off’ and the immune system reset. The same hormone, NPY, that activates the sentry cells now prompts the TH1 cells to slow down and die.

“Under normal conditions, circulating immune cells produce small amounts of NPY, which enables the immune cells on sentry duty and the TH1 immune cells to operate – it’s a yin and yang kind of situation. But too much NPY means that the TH1 attack is prevented despite the foreign invaders being identified – and this is what happens during stress,” added McKay.

The impact of stress on the body has been observed in athletes. Ph. D researcher at the University of Queensland, Luke Spence, together with the Australian Institute of Sport, studied elite and recreational athletes over five months.

They found elite athletes were more susceptible to respiratory diseases under stress.

“A lot of elite athletes put themselves through vast amounts of physical stress in their training, but also their emotional, psychological stress of feeling the pressure of Australia on their shoulders, wanting to compete and wanting to do their best,” said Spence.

It’s not just athletes who are prone to stress. Pressures at work and at home may cause emotional and mental stress that can be equally damaging. Almost a third of all work absenteeism in Australia is due to illness, costing employers over $10 billion a year.

“I think it has a huge impact for the work force and also for employers – if their employees are constantly stressed, constantly under pressure, they are more likely to get sick,” Spence said.

Further research could lead to the development of new drugs which may inhibit the action of the neuropeptide Y hormone.

Herzog warns people to minimise stress before it becomes a problem.

“Relaxation methods like yoga will help you to prevent that but there will still be people out there that are not responding to that and treatment by interfering with the system will be important,” he said. “There’s obviously some time until such a treatment will be available but this is something we will definitely work towards.”

The Garvan research will be published in the Journal of Experimental Medicine, Volume 202, No. 11.

A compilation of brief news reports for Friday, May 15, 2009.

California governor Arnold Schwarzenegger proposed budget cuts and layoffs for California yesterday.

Californian education budgets would be cut by $3 billion USD for the next five years if California voters gave a yes votes to the budget-related measures for May 19’s special election.

Schwarzenegger is also ready to sell state properties including the San Quentin State Prison and the Los Angeles Coliseum to raise money for the state.

Sources

• Associated Press. “Schwarzenegger Proposes Layoffs, Deep Budget Cuts” — FOXNews.com, 14 May 2009
• Christie, Jim. “California governor sees $15.4 billion gap, urges deep cuts” — Reuters, 14 May 2009

Nintendo DS sales hit one million units last April. However, even with Nintendo’s moderate success with their DS gaming system, all video game sales have declined 17%.

GameSpot writer Tor Thorsen claims that Nintendo DSi, the current release of the Nintendo DS, is an acronym for “Dominating Sales in America.”

Sources

• Thorsen, Tor. “NPD: US April sales slide 17%, DS tops 1 million” — GameSpot, 14 May 2009
• “UPDATE 1-U.S. video game sales down 17 pct in April-NPD” — Reuters, 14 May 2009

Eight-time gold medalist Michael Phelps, in a recent conference Thursday, told reporters he will enter a swimming competition today.

This is Phelps’ first swim meet since he was photographed with a marijuana pipe in his mouth.

Phelps will swim the 200-meter freestyle and 100-meter butterfly races.

After the marijuana pipe photo was released, Phelps was unsure of whether he would swim again.

Sources

• Crouse, Karen. “Phelps Has Company on Comeback Trail in Charlotte” — The New York Times, 14 May 2009
• Newberry, Paul. “Phelps ready for 1st race since Beijing” — Associated Press, 14 May 2009

Thursday, February 9, 2017

On Monday, scientists from the Stanford University School of Medicine announced the invention of a new diagnostic tool that can sort cells by type: a tiny printable chip that can be manufactured using standard inkjet printers for possibly about one U.S. cent each. Lead researchers say this may bring early detection of cancer, tuberculosis, HIV and malaria to patients in low-income countries, where the survival rates for illnesses such as breast cancer can be half those of richer countries.

Existing methods tend to identify cell types using fluorescent or magnetic labels, which take time to attach, but this platform uses the phenomenon of dielectrophoresis: because different kinds of cells have different levels of receptivity to electrical fields, a trait called polarizability, when an electric potential gradient is activated around the chip, different cells are pulled in different directions at different speeds. This allows doctors to diagnose cancer by determining the number of tumor cells in a patient’s blood sample. Different chips can be printed to diagnose different diseases.

Physically, the scientists say, the system has two parts. Cells are held in a clear microfluidic chamber made of silicone. The chip itself is an electronic strip that can be printed onto flexible polyester. Most lab-on-a-chip devices must be manufactured by professional staff in specialized facilities called clean rooms and can take weeks, but the chip component of this system can be made almost anywhere in as little as twenty minutes. The chips cost approximately one U.S. cent to produce (US$0.01) and can be reused. For comparison, a standard flow cytometry machine can cost US$100,000 to purchase.

“Enabling early detection of diseases is one of the greatest opportunities we have for developing effective treatments,” said lead author and electrical engineer Dr. Rahim Esfandyarpour. “Maybe $1 in the U.S. doesn’t count that much, but somewhere in the developing world, it’s a lot of money.”

Senior author Dr. Ron Davis of the Stanford University Genome Technology Center compared this invention to that of low-cost genome sequencing, which helped lead to personalized medicine.

The findings appeared in the Proceedings of the National Academy of Sciences on Monday.

Saturday, April 30, 2005

The British Food Standards Agency (FSA) has announced a recall of foods containing banned dyes which increase the risk of cancer. The food products were sold at the Tesco, Waitrose, and Somerfield supermarkets.

A Bristol company called “Barts Spices” found the illegal Para Red substance in their Barts Ground Paprika, which was sold in 48g and 46g jars with a “Co-op” label. The batch codes on the affected products are 5032 and 5089 (expiration Dec 2007), and 5075 (expiration February 2007).

Tesco also found that their 130g package of BBQ rice cakes (expiration November and December 2005) contained both Para Red and Sudan I.

“It would be very prudent to assume that it could be a genotoxic carcinogen,” FSA scientific advisers told reporters.

“As a company committed to supplying only the very finest quality food ingredients, we took the immediate decision to withdraw our ground paprika spice from all outlets selling the product and advertised a product recall in the national press,” a Barts Spices spokesman said in a statement.

Sudan I is only authorized for industrial use to colorize petroleum products, such as shoe polish. Para Red and Sudan I are banned under the British Colours in Food Regulations of 1995.

Britain last went through a major food recall in February, when Worcester Sauce was found to contain chili powder dyed with Sudan 1.

Thursday, November 2, 2006

London resident Roland De Wolfe, will take a Euro 554 300 credit boost this week after winning the European Poker Tour (EPT) in Dublin.

With a victory at the World Poker Tour (WPT) in Grand Prix de Paris already under his belt, this latest win makes him the first person to be both an EPT and WPT champion.

“This week I didn’t have the luck of the Irish, I had the luck of the whole of Europe”, De Wolfe said. “It’s an honour to be the first person to win an EPT title and a WPT title when there are so many good players out there. I’m thrilled”.

The Dublin EPT event brought up a field of 389 players from around the globe, De Wolfe managed to outplay the entire field to gain his champion slice of the Euro 1,847,750 prize pool.

Fighting for the top prize or at least a slice of the Euro 1 847 750 prize pool were many international players, and the final table was made up of U.K. players Rob Yong, Gavin Simms, and Nick Slade as well as William Thorson, of Sweden; George McKeever, from Ireland; and Patrick Bueno and David Tavernier, both from France.

Some other poker professionals that participate in the event included Simon Trumper, the Hendon Mob, Greg Raymer, Mel Judah, Chris Moneymaker, Andy Black, David Colclough, Tony Guoga.

The final rankings were as follows:

• 1st Roland De Wolfe Euro 554,300
• 2nd David Tavernier Euro 314,120
• 3rd William Thorson Euro 184,780
• 4th Gavin Simms Euro 138,580
• 5th George McKeever Euro 112,710
• 6th Rob Yong Euro 88,690
• 7th Nick Slade Euro 70,210
• 8th Patrick Bueno Euro 51,740

The next EPT will take place in Copenhagen, Denmark, from January 17 to January 20 2007.

Friday, November 13, 2009

Italian goalkeeper Carlo Cudicini has been seriously injured in a motorcycle accident in London. The player, who plays for Tottenham Hotspurs, was involved in a collision with a car at 10:30 GMT. The football club reported that he has fractured his wrists and injured his pelvis.

A spokesperson for the Metropolitan Police released a statement saying “A 36-year-old male suffered injuries described by the London Ambulance Service as possibly life-changing and was taken to Whipps Cross Hospital for further assessment and treatment”. No arrests have been made.

Cudicini crashed his motorcycle into a Ford Fiesta with a female driver and a child passenger. Neither the driver or passenger were injured in the accident.

Cudicini is the son of former AC Milan goalkeeper Fabio Cudicini. During his career he has played for Lazio, AC Milan and Chelsea. He played for Chelsea for 10 years until he was transferred to Tottenham in January. He made one appearance for the Italian national team.