New drug for smoking cessation is under investigation

Tuesday, August 15, 2006

A recent study published in the latest issue of the scientific medical journal, Archives of Internal Medicine reports on the potential use of a new drug varenicline to help smokers quit the habit. Varenicline received FDA approval for sale earlier this year.

Tobacco use remains the leading preventable cause of disease and death in the United States as well as other Western countries. The addictive habit causes approximately 440,000 deaths in the U.S. each year and costs approximately $157 billion per annum in health-related economic losses. In 2000, 70 percent of those who smoked wanted to quit smoking. Each year over half of all daily smokers try to quit. But long term success rates are generally not over 40 percent.

In a multicenter, randomized, double-blind phase II clinical trial, 638 men and women aged 18-65 who smoked an average of 10 cigarettes per day during the previous year, without a period of abstinence of more than 3 months, where put on placebo, bupropion (another drug used as a smoking cessation aid, brand name Zyban®), or different treatment schedules of varenicline for 7 weeks. Subjects were tested for continuous quitting by measuring exhaled carbon monoxide. After one year, the success rates were 14.4%, 6.3% and 4.9% for varenicline, bupropion and placebo, respectively.

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Off Road Carts

How To Discover What Really Makes You Happy

When you’re not happy even though you have everything you thought would make you happy, it’s time to take a step back and get to know yourself.When you know who you are, what your value system is and take notice of what fills you with emotions of joy and pleasant sensations, you’ll be ready to plot your course to true happiness.Getting to know yourself can be difficult. You’ve likely formed an opinion about yourself and what makes you happy, driven, sad, angry and self-confident. You may be surprised to find that what you thought was true isn’t true at all.Self-discovery can be a launching pad to happiness in your life. When you understand what you want out of life, who you’re meant to be and your true purpose, you’ll be well on your way to completing the circle of happiness.

Assessing various parts of your life can be helpful in determining your level of happiness. One way is to keep a gratitude journal. Each day, write down everything you’re grateful for. It could be something as simple as a beautiful sunrise – or as serious as a positive health report.How about your job? Are you happy with your career accomplishments or would a different route make you happier and more content? If you want to do more in that area, contemplate ways you could reach that goal. It’s best to write these thoughts and actions down to have a clear and well-defined path.

[youtube]http://www.youtube.com/watch?v=M46JlX8Fcfo[/youtube]

Find your core values and you’ll find the essence of your personality. If you’re engaged in activities or have relationships with others who don’t meet the criteria that exemplifies your true values, find a way to rid yourself of these negatives and surround yourself with positive people who adhere to those values you hold dear.Assessing your health and physical well-being is another way to discover what makes you happy. If you lack discipline to exercise and stick to a healthy eating plan to regulate your weight and fitness, figure out how doing so will make you happy.You will be more enthusiastic about becoming fitter and healthier if you know how those changes will affect your happiness quotient.Begin today to allow yourself time to think about how you define happiness. When you’re ready, begin the journey and change your path if needed.

I have a special gift for you to support you on your journey to living a life filled with more energy, happiness and success.

You can access it here >>> 5 Powerful Steps to Creating a Life Full of Energy and Vitality

Category:Tattoos

This is the category for tattoos, a form of body modification using ink and a needle.

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  • 21 June 2011: Jackass star Ryan Dunn dies in car accident aged 34
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Category:Mining

This is the category for mining.

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  • 10 January 2020: Greek prime minister reaffirms EastMed pipeline project is open for other countries to join
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Forex Broker

Learning How To Trade Penny Stocks

By Mike J. Rogers

A lot of people who hear about penny stocks would like to learn about

how to trade penny stocks

. Well, this is expected because the inexpensive price of penny stocks offers a great opportunity for anyone who wants to enter into stocks. While it’s very easy to invest in penny stocks, it is also very easy to let go of that investment because of the risks associated with it. Therefore, if you are interested in investing in penny stocks, make sure you learn how to trade penny stocks.

Penny stocks are extremely cheap stocks traded by relatively new businesses or companies facing bankruptcy. They are available for trading via Pink Sheets and Over-the-Counter Bulletin Board. Major stock exchanges such as AMEX, NYSE, and NASDAQ trade them because of their very few shareholders. Because of the high risk involved in trading penny stocks, the trading is irregular and you will realize that when you already own them, they can be hard to sell.

[youtube]http://www.youtube.com/watch?v=BUf5xd2-2C0[/youtube]

When learning how to trade penny stocks, you have two options. You can either contact a penny stock broker or search online. When doing so, you need to remember that penny stocks are not often traded by major stock exchanges. However, you will surely be enticed with their extremely inexpensive price which is a lot more investible than other stocks. This is the reason why a lot of people would like to invest on penny stocks. Stock brokers are very much aware of this.

Thus, if you want to learn how to trade penny stocks, you should turn to them for help. A stock broker has enough knowledge on analyzing and evaluating your financial situation. He/she will assess this to determine if you should invest on high-risk and speculative securities. Just make sure to look for a reputable and honest stock broker to help you learn how to trade stocks.

It is also possible to learn and master how to trade penny stocks through online sites that offer useful information on this form of stocks. Just be aware that fraud is common when dealing with penny stocks online. This is because a lot of companies offering penny stocks do not reveal the accurate information about the financial situation of the company.

When looking for sites for information on penny stocks, make sure the site has the accurate information. Because penny stocks are offered by companies that are either new or on the verge of bankruptcy, you will not always find good information about the company. If the site always offers great financial information about the company, chances are the site is not a good site to trust.

It has been said again and again – penny stocks are a great investment but you have to remember that it’s risky and highly-speculative. Thus, you need to be ready to do your job of making your own research to make sure that your investments are at a safe place. Part of your job is also to master

how to trade penny stocks

because only through this will you benefit from the investment you made.

About the Author: Do you want to learn more about how to

trade penny stocks

? Then stop by Mike Roger’s site where you can find out all about penny stock trading.

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Satanism: An interview with Church of Satan High Priest Peter Gilmore

Monday, November 5, 2007

In the 1980’s and the 1990’s there were multiple allegations of sexual abuse of children or non-consenting adults in the context of Satanic rituals that has come to be known as The Satanic Panic. In the United States, the Kern County child abuse cases, McMartin preschool trial and the West Memphis 3 cases garnered worldwide media coverage. One case took place in Jordan, Minnesota, when children made allegations of manufacturing child pornography, ritualistic animal sacrifice, coprophagia, urophagia and infanticide, at which point the Federal Bureau of Investigation was alerted. Twenty-four adults were arrested and charged with acts of sexual abuse, child pornography and other crimes related to satanic ritual abuse; only three went to trial with two acquittals and one conviction. Supreme Court Justice Scalia noted in a discussion of the case, “[t]here is no doubt that some sexual abuse took place in Jordan; but there is no reason to believe it was as widespread as charged,” and cited the repeated, coercive techniques used by the investigators as damaging to the investigation.

One of the most visible Satanic organizations—though one that was never a suspect or charged in any of the Satanic Panic cases—is the Church of Satan, founded by Anton LaVey. Members of the Church, such as Peter H. Gilmore, Peggy Nadramia, Boyd Rice, Adam Parfrey, Diabolos Rex, and musician King Diamond, were active in media appearances to refute allegations of criminal activity and the FBI would later issue an official report debunking the criminal conspiracy theories of this time.

Gilmore feels Satanists are often misunderstood or misrepresented. LaVey’s teachings are based on individualism, self-indulgence, and “eye for an eye” morality, with influence from Friedrich Nietzsche and Ayn Rand; while its rituals and magic draw heavily from occultists such as Aleister Crowley. They do not worship—nor believe in—the Devil or a Christian notion of Satan. The word “Satan” comes from the Hebrew word for “adversary” and originated from the Abrahamic faiths, being traditionally applied to an angel. Church of Satan adherents see themselves as truth-seekers, adversaries and skeptics of the religious world around them.

On a windy October day in Central Park, Wikinews reporter David Shankbone sat down with the High Priest of the Church, Peter H. Gilmore, who has led LaVey’s congregation of Satanists since his passing in 1997 (he became the High Priest in 2001). They discussed the beliefs of the Church, current events, LaVey’s children and how Satanism applies to life and the world.

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Ropes And Cords

Choosing The Right Hard Drive

Choosing the Right Hard Drive

by

dawnhobbsHow much memory and storage space do I need for my new PC? Should I opt for removable storage instead? What is a gigabyte anyway? If you find yourself asking these questions, don’t get discouraged. Buying the right hard drive requires research, thought, and a lot of patience. There are a lot of hard drives out there – this article will help you narrow down your search and pick the hard drive that’s right for you. First, you must determine whether you need an internal or external hard drive. If you’re looking for the easiest way to add data storage capacity to your computer, then you should go with an external hard drive. They’re great for backing up your PC, and they allow you to easily share photos, videos, and songs with others. Ideal for those who travel, external hard drives are physically very small so you can take them with you wherever you go.On the other hand, internal hard drives are designed for replacing or expanding the storage of a single PC. They offer massive storage capabilities, the highest performance, and the lowest cost per gigabyte. Most desktop PC cases have at least one internal drive bay (the place where you can mount extra hard drives). However, before you purchase an additional drive for your system, make sure your case has enough room. If you have a smaller, low-profile case, you won’t be able to use the old and new drives simultaneously. You’ll also have to choose between the two interfaces: PATA (Parallel Advanced Technology Attachment, also known as IDE drives) and SATA (Serial Advanced Technology Attachment). In most cases, SATA drives are a better choice for a few reasons-they’re slightly faster, they’re easier to connect, and they don’t require you to configure jumpers as PATA drives do. Nonetheless, the performance tends to be similar.The next thing you need to do is determine the size of the hard drive, which simply refers to its data storage capacity. For the most part, the size of the hard drive depends on what you plan to do with your computer. If you’re just browsing the web or doing a little word processing, you probably don’t need more than 8-10 gigabytes. The lower capacity drives are typically less expensive and should only be used to handle basic computing needs. But if you plan on storing large amounts of data, music, or pictures, you’ll want to go with a larger hard drive to avoid running out of space. Next, you must choose the speed of the hard drive, which is measured in revolutions per minute (RPM). Hard drives consist of a disc that rotates and a needle which reads/writes data to this disc. The faster the disc spins, the faster the data is read and written. For the average user, 5400 RPM is perfectly adequate. But if you want your system to be as fast as possible, then choose a hard drive with 7200 RPM. General Tips:Shop around. Hard drives come in different sizes to suit different storage needs, and they’re priced very competitively. So spend a little time searching for a killer deal, and you’ll certainly be glad you did. Look out for warranties. In general, you should get at least a 3-year warranty on your hard drive. Consider buying a hard-drive kit, which includes mounting hardware, cables, detailed instructions, and software that eases installation. A kit may also include an application for cloning the contents of your old hard drive onto the new one, which then becomes your new main drive.If you’ve outgrown your existing storage, it may be easier and cheaper to upgrade a drive instead of buying an entirely new one. And if you’re an avid gamer, opt for a drive with approximately 10,000 RPM.hard drivesexternal hard driveinternal hard drives

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[youtube]http://www.youtube.com/watch?v=qO-JaiY0U9M[/youtube]

Category:Frogs

This is the category for frogs.

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  • 16 June 2009: Study says nearly every species of animal engages in homosexual behavior
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Australian refugee contractor accused of breaching its duty of care

Friday, December 30, 2005

The Australian Centre for Languages, a company which has a multi-million dollar contract with the Australian government to provide refugee services, has been accused of breaching its duty of care following the death of a chronically ill child and allegations of failing to provide three women in their care with food.

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Insurance

Consolidate Private Student Loans With Fixed Interest Rate How To Guide

By Larry Donaldson

If you took out multiple private student loans while in college, you are probably now swimming in a sea of paperwork each month. Having more than one student loan often means having to make payments to different lenders at different times of each month.

Another common challenge is that some your private loans may have variable interest rates, while others have fixed rates. And, it is highly likely that your loans are at different interest rates altogether.

Besides the complexity of having multiple private student loans to deal with, most grads also have trouble making the payments. Having to be responsible for multiple student loan payments is not something that many college students give much thought to during school. But, once graduation is over, reality sets in. And, the payments can easily run into the hundreds of dollars or more each month.

When Private Student Loan Consolidation Makes Sense

For graduates who have taken out multiple student loans and are now having trouble making their loan payments each month, private student loan consolidation can help.

Simply put, consolidation is the act of paying off all of one’s outstanding loans in full with the money received with from new, consolidation loan.

[youtube]http://www.youtube.com/watch?v=H1w7Xq0E8Jc[/youtube]

How Can Consolidation Help?

Consolidation loans can be helpful in many ways. First, they simply your life by making you responsible for just a single payment each month.

Next, they can actually lower your payments in one or both of two ways:

a. By lowering your rate

b. By stretching out your payments over more time, say from 10 years to 20 or 30 years.

Finally, consolidation loans can be negotiated at a fixed rate, which means you can lock in your new low rate over the life of the loan.

How To Consolidate Private Student Loans With A Fixed Interest Rate

If you are wondering how to get the best deal on a fixed interest rate private consolidation loan, here are some tips that can help:

1.Calculate your current interest rate: In order to determine whether any would-be offer you get is worth going for, you are going to want to start by figuring out the weighted average of your existing loans’ rates. For example, if you currently have three loans at 5%, 3% and 2.5% interest rates, you would calculated the weighted average interest rate as follows.

First, figure out what percentage of your total outstanding balance is represented by each loan. Let’s say that the answer is 20%, 30% and 50%, respectively. Just multiply these percentages by the interest rate for each loan and add them together, as follows:

(20% x 5%) + (30% x 3%) + (50% + 2.5%) = weighted average interest rate

2. Figure out your ideal repayment period: Use an online loan calculator and plug in your current outstanding balance (total across all loans) and your desired new interest rate. Then, plug in different repayment periods like 20 years, 25 years and 30 years. See how each one affects both the monthly payment amounts and the cost of your loan.

3. Build a list of at least 5 private consolidation lenders: Now, it’s time to do your research. Make a list of at least 5 lenders. Don’t skip this step – remember, more offers is always better than fewer!

4. Contact and apply with all 5 lenders: Now, take the time to contact and actually apply for a consolidation loan with each lender. hint: be sure to apply for the same repayment period so that you can compare the offers equally.

5. Compare offers: Compare each offer you get separately, and be sure to read the fine print. The most important piece of information to look at is the interest rate of each offer.

Follow these tips to get the best-possible deal on a fixed interest rate loan.

About the Author: Find more info and helpful tips on private student loan consolidation at:

Best Private Student Loan Consolidation

.

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